Wednesday 14 December 2022
Global Solar Irradiation Modelling and Prediction Using Machine Learning Models for Their Potential Use in Renewable Energy Applications
Monday 12 December 2022
This article belongs to the Special Issue Host-Guest Complexes and corresponds with the special issue editorial. In this Special Issue, we hope to address both the structural aspects of the formation and stability of these inclusion complexes as well as the energetic aspects associated with them, together with the different instrumental techniques used to characterise them, addressing the aspects related to molecular recognition and conformational switching. Of course, we must also take into account the aspects related to the technological applications of these compounds. In fact, they show important potentialities in topics such as superconductivity phenomena, the design of sensors, and food chemistry, agricultural chemistry, or their applications in matters of the environment.
Friday 2 December 2022
Thursday 1 December 2022
Prospecting the role of nanotechnology in extending the shelf-life of fresh produce and in developing advanced packaging
Wednesday 30 November 2022
Científicos, palangreiros e administración poñen en valor os beneficios nutricionais do consumo das grandes especies peláxicas
Presentáronse os resultados dun estudo do Grupo de Investigacións Agroambientais e Agroalimentarias sobre catro especies “ricas en proteínas de alto valor biolóxico” e ácidos graxos poliinsaturados.
Wednesday 16 November 2022
- Lugar: Salón de Graos do Edificio Politécnico do Campus de Ourense
- Data: xoves, 17 de novembro de 2022
- Hora: ás 17.00h
- 17.00h Presentación
- 17.10h O piollo do salmón: xaque á salmonicultura
Dr. Raúl Iglesias Blanco (Profesor da área de Parasitoloxía na Universidade de Vigo)
- 17.45h Inicio do Proxecto MicroMundo@UVigo3.0: aprendizaxe-servizo para a busca de microorganismos produtores de novos antibióticos(Curso2022-2023)
Dra. Julia Carballo Rodríguez (Profesora da área de Microbioloxía e Instructora MicroMundo na Universidade de Vigo)
- 18.15h Mesa redonda sobre a participación no proxecto MicroMundo@UVigo
Participantes: Dna. María José Rodríguez Fernandez (Tutora, IES O Couto)
Alumnado do IES O Couto
D. Tomás González Rivas (Alumno da Facultade de Ciencias)
Dna. Julia Carballo Rodríguez (Instructora, Facultade de Ciencias)
- 19.00h Clausura
Wednesday 9 November 2022
“Ficus carica L.” and its by-products: A decade evidence of their health-promoting benefits towards the development of novel food formulations
Wednesday 2 November 2022
Tuesday 1 November 2022
Thursday 27 October 2022
Nanobiotechnology has recently gained prominence as a fundamental branch of modern science and a novel epoch in the field of material researches. Due to a wide range of applications it attracts attention of many scientists from all over the world. Bionanomaterials are prepared using a variety of physical, chemical, and biological techniques and methods. Many different metal and metal oxide nanoparticles are reported to be produced by biological systems, including bacteria, fungi, actinomycetes, yeasts, viruses, and plants. Among all of them, biocompatible zinc oxide nanoparticles (ZnO NPs), obtained through biosynthesis with the aid of plant-derived materials, appears to be a highly successful way to create a fast, clean, non-toxic, and environmentally friendly platform for the production and application of these bionanomaterials. This review focuses on the plant extract-derived ZnO NPs synthesis, with a special emphasis on the recent advances and applications of these nanomaterials.
Wednesday 26 October 2022
Sunday 23 October 2022
The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis
Saturday 22 October 2022
Tuesday 18 October 2022
During the previous few years, the relationship between the gut microbiota, metabolic disorders, and diet has come to light, especially due to the understanding of the mechanisms that particularly link the gut microbiota with obesity in animal models and clinical trials. Research has led to the understanding that the responses of individuals to dietary inputs vary remarkably therefore no single diet can be suggested to every individual. The variations are attributed to differences in the microbiome and host characteristics. In general, it is believed that the immanent nature of host-derived factors makes them difficult to modulate. However, diet can more easily shape the microbiome, potentially influencing human physiology through modulation of digestion, absorption, mucosal immune response, and the availability of bioactive compounds. Thus, diet could be useful to influence the physiology of the host, as well as to ameliorate various disorders. In the present study, we have described recent developments in understanding the disparities of gut microbiota populations between individuals and the primary role of diet-microbiota interactions in modulating human physiology. A deeper understanding of these relationships can be useful for proposing personalized nutrition strategies and nutrition-based therapeutic interventions to improve human health.
Monday 17 October 2022
The current global changes in economic, social, and technological production systems of food necessitate developing innovative solutions and strategies that ensure maximum utilization of food resources to produce desirable and wholesome food products. Food chemistry and related research activities are arguably the core of research activities that ensure the achievement of the above goals. This Research Topic is aimed at capturing prominent food chemistry research activities to provide recent insights and current research activities to meet the above goals. This Research Topic provides a balanced collection of original research, reviews, and new methods contributions, authored by experts in the field. The studies reported in the present Research Topic can be generally categorized into the following themes: food safety research that was concerned with the detection and quantification of pesticides and antimicrobial agents; studies on bioactive compounds, their stability and biofunctionalities; fractionation of pea protein, and others.
Sunday 16 October 2022
Comparison of Chromatic and Spectrophotometric Properties of White and Red Wines Produced in Galicia (Northwest Spain) by Applying PCA
Tuesday 11 October 2022
Advances in Fungal Phenaloenones—Natural Metabolites with Great Promise: Biosynthesis, Bioactivities, and an In Silico Evaluation of Their Potential as Human Glucose Transporter 1 Inhibitors
Phenaloenones are structurally unique aromatic polyketides that have been reported in both microbial and plant sources. They possess a hydroxy perinaphthenone three-fused-ring system and exhibit diverse bioactivities, such as cytotoxic, antimicrobial, antioxidant, and anti-HIV properties, and tyrosinase, α-glucosidase, lipase, AchE (acetylcholinesterase), indoleamine 2,3-dioxygenase 1, angiotensin-I-converting enzyme, and tyrosine phosphatase inhibition. Moreover, they have a rich nucleophilic nucleus that has inspired many chemists and biologists to synthesize more of these related derivatives. The current review provides an overview of the reported phenalenones with a fungal origin, including their structures, sources, biosynthesis, and bioactivities. Moreover, more than 135 metabolites have been listed, and 71 references have been cited. SuperPred, an artificial intelligence (AI) webserver, was used to predict the potential targets for selected phenalenones. Among these targets, we chose human glucose transporter 1 (hGLUT1) for an extensive in silico study, as it shows high probability and model accuracy. Among them, aspergillussanones C (60) and G (60) possessed the highest negative docking scores of −15.082 and −14.829 kcal/mol, respectively, compared to the native inhibitor of 5RE (score: −11.206 kcal/mol). The MD (molecular dynamics) simulation revealed their stability in complexes with GLUT1 at 100 ns. The virtual screening study results open up a new therapeutic approach by using some phenalenones as hGLUT1 inhibitors, which might be a potential target for cancer therapy.
Saturday 8 October 2022
Royal Jelly: Beneficial Properties and Synergistic Effects with Chemotherapeutic Drugs with Particular Emphasis in Anticancer Strategies
Cancer is one of the major causes of death globally. Currently, various methods are used to treat cancer, including radiotherapy, surgery, and chemotherapy, all of which have serious adverse effects. A healthy lifestyle, especially a nutritional diet, plays a critical role in the treatment and prevention of many disorders, including cancer. The above notion, plus the trend in going back to nature, encourages consumers and the food industry to invest more in food products and to find potential candidates that can maintain human health. One of these agents, and a very notable food agent, is royal jelly (RJ), known to be produced by the hypopharyngeal and mandibular salivary glands of young nurse honeybees. RJ contains bioactive substances, such as carbohydrates, protein, lipids, peptides, mineral salts and polyphenols which contribute to the appreciated biological and pharmacological activities. Antioxidant, anticancer, anti-inflammatory, antidiabetic, and antibacterial impacts are among the well-recognized benefits. The combination of RJ or its constituents with anticancer drugs has synergistic effects on cancer disorders, enhancing the drug’s effectiveness or reducing its side effects. The purpose of the present review is to emphasize the possible interactions between chemotherapy and RJ, or its components, in treating cancer illnesses.
Friday 7 October 2022
The Chemical, Microbiological and Volatile Composition of Kefir-like Beverages Produced from Red Table Grape Juice in Repeated 24-h Fed-Batch Subcultures
The aim of this work was to study the production of kefir-like beverages via the fed-batch fermentation of red table grape juice at initial pHs of 3.99 (fermentation A) and 5.99 (fermentation B) with kefir grains during 4 repeated 24-h fed-batch subcultures. All kefir-like beverages (KLB) were characterized by low alcoholic grade (≤3.6%, v/v) and lactic and acetic acid concentrations. The beverages obtained from fermentation B had lower concentrations of sugars and higher microbial counts than the KLB obtained in fermentation A. Additionally, the KLB samples from fermentation B were the most aromatic and had the highest contents of alcohols, esters, aldehydes and organic acids, in contrast with the nonfermented juice and KLB from fermentation A. These results indicate the possibility of obtaining red table grape KLB with their own distinctive aromatic characteristics and high content in probiotic viable cells, contributing to the valorization of this fruit.
Thursday 6 October 2022
Phytochemical Profiling, Mineral Elements, and Biological Activities of Artemisia campestris L. Grown in Algeria
Artemisia campestris L. is commonly used in folk medicine due to its antioxidant, antidiabetic, nutritional, and culinary properties. Our study assessed the total phenolics contents, antioxidant, and pharmacological activities of various organic extracts prepared from the aerial parts of Artemisia campestris, and its mineral elements and chemical profile were analyzed. ICP-OES was used to analyze the mineral profile and the LC-MS/MS analysis was used to characterize the phytochemical profiling. A series of antioxidant tests were carried out using DPPH, ABTS, beta-carotene, GOR, RP, CUPRAC, and O-Phenanthroline assays. In vitro potent inhibitory actions of A. campestris extracts were investigated to evaluate their anti-cholinesterase, anti-lipase and anti-diabetic activities. The photoprotective effect of the plant was measured by the sun protection factor. The most powerful inhibitor of α-amylase was AcPEE (IC50 = 11.79 ± 0.14 μg/mL), which also showed a significant butyrylcholinesterase inhibitory effect (IC50 = 93.50 ± 1.60 μg/mL). At IC50 = 23.16 ± 0.19 μg/mL, AcEAE showed the most powerful inhibitory effects on acetylcholinesterase. A. campestris was found to have a strong photoprotective ability, absorbing UV radiations with SPF values ranging from 26.07 ± 0.22 to 40.76 ± 0.11. The results showed that A. campestris extract has strong antioxidant activity in all the test samples except for the carotene bleaching assay. The LC/MS-MS results showed that AcDE, AcEAE, and AcBE identified 11 compounds belonging to Polyphenols Compounds. Our result also showed that A. campestris contains a high concentration of essential minerals, including macro-and micro-elements with their values close to the FAO’s recommended concentration. A. campestris has the capacity to improve pharmaceutical formulations, health, and medical research, due to its compositions and potent biological properties.
Tuesday 4 October 2022
Identification of novel natural drug candidates against BRAF mutated carcinoma; An integrative in-silico structure-based pharmacophore modeling and virtual screening process
Saturday 1 October 2022
Friday 30 September 2022
Crosstalk between xanthine oxidase (XO) inhibiting and cancer chemotherapeutic properties of comestible flavonoids- a comprehensive update
Monday 26 September 2022
Papaya is one of the most important fruit trees cultivated throughout the tropical and subtropical regions and its production is rising worldwide. Its edible part has a high nutritional and sensory value and a great commercial potential. Mature papaya is consumed fresh and has been used in food processing and cosmetic industries. Along with some other parts such as leaves, seeds or skin, papaya has been used in traditional medicine in various countries. In fact, numerous studies have reported the presence of bioactive compounds with diverse biological properties in the papaya by-products, which has motivated the expansion of their applications. Papaya by-products have been demonstrated to exert a wide range of activities (e.g.; antioxidant, anti-cancer, anti-dengue, anti-malarial, anti-fertility, diabetes prevention, insecticidal, anti-AIDS) that could be useful in pharmaceutical industry. They could be used in food industry, as a source of functional compounds and in innovative active packaging strategies, and in different cosmetic products, among other applications. Although this scenario indicates that the papaya industry could diversify and increase its economic value, there are two problems that significantly affect it: the spread of pathogens and the highly perishable nature of this fruit. On the one hand, genetic tools have been used to obtain transgenic varieties resistant to pathogens, while new preservation technologies have been explored. This review focuses on the main bioactive compounds, important physiological functions and applications of different papaya parts and also in the current development of genetically modified papaya in the industry and the research progress on storage and preservation.
Thursday 22 September 2022
Friday 16 September 2022
Enrichment of gamma-aminobutyric acid in foods: From conventional methods to innovative technologies
Wednesday 14 September 2022
Himalayan Wild Fruits as a Strong Source of Nutraceuticals, Therapeutics, Food and Nutrition Security
Tuesday 13 September 2022
The constant increment in the world’s population leads to a parallel increase in the demand for food. This situation gives place the need for urgent development of alternative and sustainable resources to satisfy this nutritional requirement. Human nutrition is currently based on fisheries, which accounts for 50% of the fish production for human consumption, but also on agriculture, livestock, and aquaculture. Among them, aquaculture has been pointed out as a promising source of animal protein that can provide the population with high-quality protein food. This productive model has also gained attention due to its fast development. However, several aquaculture species require considerable amounts of fish protein to reach optimal growth rates, which represents its main drawback. Aquaculture needs to become sustainable using renewable source of nutrients with high contents of proteins to ensure properly fed animals. To achieve this goal, different approaches have been considered. In this sense, single-cell protein (SCP) products are a promising solution to replace fish protein from fishmeal. SCP flours based on microbes or algae biomass can be sustainably obtained. These microorganisms can be cultured by using residues supplied by other industries such as agriculture, food, or urban areas. Hence, the application of SCP for developing innovative fish meal offers a double solution by reducing the management of residues and by providing a sustainable source of proteins to aquaculture. However, the use of SCP as aquaculture feed also has some limitations, such as problems of digestibility, presence of toxins, or difficulty to scale-up the production process. In this work, we review the potential sources of SCP, their respective production processes, and their implementation in circular economy strategies, through the revalorization and exploitation of different residues for aquaculture feeding purposes. The data analyzed show the positive effects of SCP inclusion in diets and point to SCP meals as a sustainable feed system. However, new processes need to be exploited to improve yield. In that direction, the circular economy is a potential alternative to produce SCP at any time of the year and from various cost-free substrates, almost without a negative impact.
Wednesday 31 August 2022
Tuesday 30 August 2022
Comparative study on the phenolic composition and in vitro bioactivity of medicinal and aromatic plants from the Lamiaceae family
Thursday 25 August 2022
The Nutritional and Bioactive Components, Potential Health Function and Comprehensive Utilization of Pomegranate: A Review
Tuesday 23 August 2022
Hepatoprotective Mechanism of Ginsenoside Rg1 against Alcoholic Liver Damage Based on Gut Microbiota and Network Pharmacology
Alcoholic liver disease (ALD) is a major public health problem worldwide, which needs to be effective prevention. Ginsenoside Rg1 (GRg1), a bioactive ingredient extracted from ginseng, has benefit effects on health. In this study, 11 potential targets of GRg1 against ALD were firstly obtained by network pharmacology. KEGG pathway enrichment showed that GRg1-target-ALD was closely related to Toll-like receptor (TLR) and nuclear factor-kappa B (NF-κB) signaling pathways. In addition, GRg1 decreased antioxidant levels and increased oxidative levels in alcohol-treated mice, which alleviated oxidative stress-induced hepatic damage. GRg1 enhanced intestinal barrier function via upregulating the levels of tight junction protein and immunoglobulin A. GRg1 also reduced alcohol-induced inflammation by suppressing TLR4/NF-κB pathway, which was consistent with the prediction of network targets. Moreover, GRg1 altered GM population, and Verrucomicrobia, Bacteroidetes, Akkermansia, Bacteroides, Lachnospiraceae_NK4A136_group, and Alloprevotella played positive association with intestinal barrier indicators and negative correlation with hepatic inflammation biomarkers. The results suggest that GRg1 administration might be a promising strategy for protection of alcohol-induced liver damage.
Wednesday 10 August 2022
Metabolomics approach reveals high energy diet improves the quality and enhances the flavor of black Tibetan sheep meat by altering the composition of rumen microbiota
Monday 1 August 2022
Safer plant-based nanoparticles for combating antibiotic resistance in bacteria: A comprehensive review on its potential applications, recent advances, and future perspective
Antibiotic resistance is one of the current threats to human health, forcing the use of drugs that are more noxious, costlier, and with low efficiency. There are several causes behind antibiotic resistance, including over-prescription of antibiotics in both humans and livestock. In this scenario, researchers are shifting to new alternatives to fight back this concerning situation.
Scope and approach
Nanoparticles have emerged as new tools that can be used to combat deadly bacterial infections directly or indirectly to overcome antibiotic resistance. Although nanoparticles are being used in the pharmaceutical industry, there is a constant concern about their toxicity toward human health because of the involvement of well-known toxic chemicals (i.e., sodium/potassium borohydride) making their use very risky for eukaryotic cells.
Key findings and conclusions
Multiple nanoparticle-based approaches to counter bacterial infections, providing crucial insight into the design of elements that play critical roles in the creation of antimicrobial nanotherapeutic drugs, are currently underway. In this context, plant-based nanoparticles will be less toxic than many other forms, which constitute promising candidates to avoid widespread damage to the microbiome associated with current practices. This article aims to review the actual knowledge on plant-based nanoparticle products for antibiotic resistance and the possible replacement of antibiotics to treat multidrug-resistant bacterial infections.